tert-butyl 4-chloropiperidine-1-carboxylate
N-BOC-4-CHLORO-PIPERIDINE
CAS: 154874-94-9
Molecular Formula: C10H18ClNO2
tert-butyl 4-chloropiperidine-1-carboxylate - Names and Identifiers
| Name | N-BOC-4-CHLORO-PIPERIDINE |
| Synonyms | N-BOC-4-CHLORO-PIPERIDINE 1-BOC-4-CHLORO-PIPERIDINE 1-Piperidinecarboxylicacid, 4-chloro- Silanecarboxamide,N,N,1,1,4-pentamethyl- tert-butyl 4-chloropiperidine-1-carboxylate 4-chloro-1-piperidinecarboxylic acid tert-butyl ester 4-Chloro-piperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-chloro-, 1,1-dimethylethyl ester |
| CAS | 154874-94-9 |
| InChI | InChI=1/C10H18ClNO2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7H2,1-3H3 |
tert-butyl 4-chloropiperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C10H18ClNO2 |
| Molar Mass | 219.71 |
| Density | 1.11±0.1 g/cm3(Predicted) |
| Boling Point | 289.7±33.0 °C(Predicted) |
| Flash Point | 129.005°C |
| Vapor Presure | 0.002mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | White |
| pKa | -2.77±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.487 |
tert-butyl 4-chloropiperidine-1-carboxylate - Risk and Safety
| UN IDs | UN2811 |
tert-butyl 4-chloropiperidine-1-carboxylate - Introduction
N-BOC-4-CHLORO-PIPERIDINE is an organic compound whose chemical structure is Cl-C6H4-N(Boc)-C5H9N. Its nature is specified as follows:
1. Appearance: White to light yellow solid.
2. Melting Point: about 40-45 ° C.
3. Solubility: Soluble in common organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
One of the main uses of N-BOC-4-CHLORO-PIPERIDINE is as an intermediate in organic synthesis. It can be used to synthesize other compounds, such as drugs, pesticides and functional materials. It can also be used as a protecting group of piperidine compounds to protect and regulate the reaction properties of the compounds.
The process for the preparation of N-BOC-4-CHLORO-PIPERIDINE usually starts from N-Boc-piperidine. First, N-Boc-piperidine is reacted with thionyl chloride to form a sulfoxide salt of N-Boc-piperidine. Then, chlorides such as thionyl chloride and Eubers chloride are reacted with the sulfoxide salt to give N-BOC-4-CHLORO-PIPERIDINE.
Regarding safety information, N-BOC-4-CHLORO-PIPERIDINE is a chemical and should be handled with caution. During use, appropriate laboratory safety procedures and personal protective measures should be followed. Be careful to avoid contact with skin, eyes and clothing, and ensure that it is used in a well-ventilated area. If accidentally inhaled or exposed to the compound, should promptly seek medical attention. Detailed safety information should refer to the safety technical specifications of the relevant chemical.
1. Appearance: White to light yellow solid.
2. Melting Point: about 40-45 ° C.
3. Solubility: Soluble in common organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane.
One of the main uses of N-BOC-4-CHLORO-PIPERIDINE is as an intermediate in organic synthesis. It can be used to synthesize other compounds, such as drugs, pesticides and functional materials. It can also be used as a protecting group of piperidine compounds to protect and regulate the reaction properties of the compounds.
The process for the preparation of N-BOC-4-CHLORO-PIPERIDINE usually starts from N-Boc-piperidine. First, N-Boc-piperidine is reacted with thionyl chloride to form a sulfoxide salt of N-Boc-piperidine. Then, chlorides such as thionyl chloride and Eubers chloride are reacted with the sulfoxide salt to give N-BOC-4-CHLORO-PIPERIDINE.
Regarding safety information, N-BOC-4-CHLORO-PIPERIDINE is a chemical and should be handled with caution. During use, appropriate laboratory safety procedures and personal protective measures should be followed. Be careful to avoid contact with skin, eyes and clothing, and ensure that it is used in a well-ventilated area. If accidentally inhaled or exposed to the compound, should promptly seek medical attention. Detailed safety information should refer to the safety technical specifications of the relevant chemical.
Last Update：2024-04-09 21:01:54
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Product Name: N-Boc-4-Chloro-Piperidine Visit Supplier Webpage Request for quotationCAS: 154874-94-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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